NeuroGenE is the Global Initiative in Neuropsychiatric GenEthics based at the University of Oxford. We conduct global multidisciplinary research and capacity-building on the ethics of novel innovations relating to psychiatry and developmental disorders. Our team based in Oxford and our collaborators investigate the ethical tensions outlined in our research vision. Working in partnership with the Stanley Center at the Broad Institute of Harvard and MIT, local bioethicists and scientists, and mental health and disability rights advocates, NeuroGenE identifies and examines the fundamental ethical questions that arise in the context of global scientific research in psychiatric genetics. NeuroGenE also leads a network that puts young people at the heart of developing a framework for responsible and relevant digital mental health interventions for young people in African countries. Our work supports the potential for novel global innovations to lead to improvements in mental health and developmental disorder research infrastructure, and in the lives of people with mental and neurodevelopmental conditions.